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31Oct2025Select date
Check-out
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Rooms and Guests2 Guests, 1 Room
Key details

Hotel overview and key features

700 West Main Street, Louisville, Kentucky, United States, 40202

21C Museum Hotel Louisville, a 5-star hotel with a 9.1/10 Booking.com rating, is located in Downtown Louisville near the Kentucky Museum of Art & Craft, Frazier International History Museum, and Muhammad Ali Center, all within a half mile. The hotel near airport offers easy access via the free electric ZeroBus, located two roads down, which circulates along Main and Market streets, passing Whiskey Row and Slugger Field.

Luxury Sleep & Space

Guest rooms at 21c Louisville feature premium Bryte Restorative Sleep Beds with customizable firmness and temperature settings. The largest room includes an open floor plan with a king-sized bed, living and dining areas, and a connecting king bedroom. Multi-purpose furniture and antique pieces like a writing desk and rocking chair complement the contemporary design.

Bourbon & Dining

Proof on Main, the hotel's on-site restaurant, serves southern and Appalachian-inspired cuisine, including bourbon-focused dishes from the 21c Selects Private Barrel Program. The Fork & Bottle dinner series features guest distillers and regional spirits, while the Hog & Barrel dinner highlights Pappy Van Winkle. Catering menus can be tailored for private events.

Art & Events

21c Louisville houses over 9000 square feet of exhibition space, showcasing contemporary art like Fragile Figures: Beings and Time. Guests can attend events such as the Fork & Bottle series or immersive performances inspired by the museum's installations. The hotel is steps from Revelry Boutique Gallery, featuring over 150 regional artists.

Wellness & Meetings

The hotel offers reflexology and sports massages, targeting reflex points and athletic recovery. Dedicated event staff assist with eco-conscious meetings, while four private galleries accommodate groups of 10 to 60. 21c Museum Hotel Louisville also provides access to River City Tintype for unique photography experiences.

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Choose your ideal room style

Choose from family rooms, suites, flexible cancellation & more
Room Balcony
2 persons
29 m² 
1 King-size bed
Shower
Coffee machine
Deluxe King Room
2 persons
31 m² 
1 King-size bed
Shower
Coffee machine
Corner Suite
2 persons
61 m² 
1 King-size bed
Shower
Coffee machine
Deluxe King Suite
2 persons
46 m² 
1 King-size bed
Shower
Coffee machine
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Prices and Availability

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Getting around

Transportation options available

City Centre
Louisville 1.9 km
Airports
Louisville (SDF) 11.9 km

Facilities

Stay relaxed and refreshed just minutes from the airport

General

  • No smoking on site
  • Free Wi-Fi
  • Parking
  • Safe deposit box
  • 24-hour reception
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Security
  • Luggage storage
  • Locker room
  • Allergy-free rooms
  • Lift
  • ATM/Cash machine
  • Smoke detectors
  • Electric vehicle charging station
  • Fire extinguishers

Sports & Fitness

  • Fitness centre
  • Yoga class

Guest Parking

  • Cookware/ Kitchen utensils

Services

  • Valet parking
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Welcome drink

Dining

  • Restaurant
  • Bar/ Lounge area
  • Outdoor dining area

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Cots

Spa & Leisure

  • Spa & wellness centre
  • Sauna
  • Turkish bath
  • Steam room
  • Full body massage

Room features

  • Air conditioning
  • Heating
  • Mini-bar
  • Soundproofed rooms
  • Patio
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries

Self-catering

  • Cookware/ Kitchen utensils

Media

  • Flat-screen TV

Room decor

  • Carpeted floor
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Location info

700 West Main Street, Louisville, Kentucky, United States, 40202
Map view
700 West Main Street, Louisville, Kentucky, United States, 40202
Nearby
Museum
Louisville Slugger Museum & Bat Factory
180 m
Museum
Muhammad Ali Center
280 m
Museum
Kentucky Science Center
140 m
Museum
The Frazier History Museum
260 m
Museum
Kentucky Museum of Art and Craft
70 m
528 W Main St
Evan Williams Bourbon Experience
200 m
Gallery
Flame Run Glass Studio and Gallery
300 m
500 W Main St
The Belvedere
250 m
Night club
Jimmy Can't Dance
90 m
801 W Main St
Michter's Fort Nelson Distillery
150 m
Library
Sons of the American Revolution Genealogical Research Library
190 m
120 N 10th St
Kentucky Peerless Distilling Co
480 m
401 W River Rd
Belle of Louisville Riverboats
580 m
Restaurants
Proof On Main
10 m
702 West Main Street
Mussel & Burger Bar Downtown
60 m
113 S 7th St Located in Louisville's Central Business District
Bristol Bar & Grille
110 m
614 W Main St
Atlantic No. 5
160 m
605 W Main St Located in Louisville's Central Business District.
Los Aztecas Mexican Restaurant
180 m
445 E Market St
Vincenzo's Italian Restaurant
430 m
150 S 5th St
Jockey Silks Bourbon Bar
480 m
140 N 4th St 2nd Floor - West Tower
Dish on Market
470 m
434 W Market St
Quiznos
540 m
223 S 5th St
Swizzle Dinner & Drinks
530 m
140 N Fourth St 25th Floor
Cafe Magnolia
590 m
140 N 4th St Galt House Hotel
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Check-in
31Oct2025Select date
Check-out
01Nov2025Select date
Rooms and Guests2 Guests, 1 Room